Cargando…

EMAP-II-dependent lymphocyte killing is associated with hypoxia in colorectal cancer

Endothelial-monocyte-activating polypeptide-II (EMAP-II) is a novel multifunctional polypeptide with proinflammatory activity. We have previously shown that the recombinant and native forms of EMAP-II can induce apoptosis in mitogen-stimulated lymphocytes, and that the release of this protein into t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Youssef, M M S, Symonds, P, Ellis, I O, Murray, J C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360520/ https://www.ncbi.nlm.nih.gov/pubmed/16929248 http://dx.doi.org/10.1038/sj.bjc.6603299

Ejemplares similares

Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia
por: Koukourakis, M I, et al.
Publicado: (2010)

Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer
por: Hector, S, et al.
Publicado: (2012)

Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases
por: Buckowitz, A, et al.
Publicado: (2005)

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis
por: Nam, S Y, et al.
Publicado: (2011)

Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer
por: Chen, Z-Y, et al.
Publicado: (2015)

Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis
por: Blick, C, et al.
Publicado: (2015)

Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer
por: Chua, W, et al.
Publicado: (2011)

Combination of platelet count and neutrophil to lymphocyte ratio is a useful predictor of postoperative survival in patients with colorectal cancer
por: Ishizuka, M, et al.
Publicado: (2013)

The intratumoural subsite and relation of CD8(+) and FOXP3(+) T lymphocytes in colorectal cancer provide important prognostic clues
por: Ling, A, et al.
Publicado: (2014)

A derived neutrophil to lymphocyte ratio predicts clinical outcome in stage II and III colon cancer patients
por: Absenger, G, et al.
Publicado: (2013)

The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue
por: Oladipo, O, et al.
Publicado: (2011)

Sentinel node lymphocytes: tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer
por: Marits, P, et al.
Publicado: (2006)

Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma
por: Kantola, T, et al.
Publicado: (2012)

Hypoxia-inducible factor-1α and -2α are expressed in most rectal cancers but only hypoxia-inducible factor-1α is associated with prognosis
por: Rasheed, S, et al.
Publicado: (2009)

Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype
por: Barathova, M, et al.
Publicado: (2008)

CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a ‘pro-/anti-tumour’ approach to tumour host interaction in colorectal cancer
por: Lugli, A, et al.
Publicado: (2009)

Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?
por: McLean, M H, et al.
Publicado: (2013)

Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer
por: Carpenter, B, et al.
Publicado: (2006)

Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
por: Hussain, S A, et al.
Publicado: (2007)

Hypoxia-associated markers in gastric carcinogenesis and HIF-2α in gastric and gastro-oesophageal cancer prognosis
por: Griffiths, E A, et al.
Publicado: (2008)

Characterisation and protein expression profiling of annexins in colorectal cancer
por: Duncan, R, et al.
Publicado: (2008)

‘Desperate house genes’: the dramatic example of hypoxia
por: Caradec, J, et al.
Publicado: (2010)

Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases
por: Kahlert, C, et al.
Publicado: (2014)

Preoperative neutrophil:lymphocyte and platelet:lymphocyte ratios predict endometrial cancer survival
por: Cummings, M, et al.
Publicado: (2015)

Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia–dysplasia–adenocarcinoma sequence
por: Griffiths, E A, et al.
Publicado: (2007)

CpG-island methylation of the ER promoter in colorectal cancer: analysis of micrometastases in lymph nodes from UICC stage I and II patients
por: Harder, J, et al.
Publicado: (2009)

Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype
por: Ameri, K, et al.
Publicado: (2010)

Prognostic implication of the CpG island methylator phenotype in colorectal cancers depends on tumour location
por: Bae, J M, et al.
Publicado: (2013)

Expression of miR-210 in relation to other measures of hypoxia and prediction of benefit from hypoxia modification in patients with bladder cancer
por: Irlam-Jones, J J, et al.
Publicado: (2016)

Intracrine VEGF signalling mediates colorectal cancer cell migration and invasion
por: Bhattacharya, Rajat, et al.
Publicado: (2017)

Tumour-infiltrating CD68+ and CD57+ cells predict patient outcome in stage II–III colorectal cancer
por: Chaput, N, et al.
Publicado: (2013)

Mimicking the tumour microenvironment of chronic lymphocytic leukaemia in vitro critically depends on the type of B-cell receptor stimulation
por: Rombout, Ans, et al.
Publicado: (2016)

No relationship between thymidine phosphorylase (TP, PD-ECGF) expression and hypoxia in carcinoma of the cervix
por: Kabuubi, P, et al.
Publicado: (2006)

Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer
por: Verset, L, et al.
Publicado: (2013)

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer
por: Wigfield, S M, et al.
Publicado: (2008)

The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
por: Ragnum, H B, et al.
Publicado: (2015)

The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance
por: Alnabulsi, Abdo, et al.
Publicado: (2017)

Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer
por: Ord, J J, et al.
Publicado: (2005)

Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix
por: Mayer, A, et al.
Publicado: (2013)

Identification of genes and pathways associated with cytotoxic T lymphocyte infiltration of serous ovarian cancer
por: Leffers, N, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_14lald2m4vokv3u9b91hcecrun