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Vinflunine: a new active drug for second-line treatment of advanced breast cancer. Results of a phase II and pharmacokinetic study in patients progressing after first-line anthracycline/taxane-based chemotherapy

To evaluate the single agent activity, pharmacokinetics and tolerability of the novel tubulin targeted agent vinflunine (VFL) (320 mg m(−2) q 21 days) as second-line chemotherapy in patients with metastatic breast carcinoma (MBC). All patients had disease progression after anthracycline/taxane (A/T)...

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Detalles Bibliográficos
Autores principales:	Campone, M, Cortes-Funes, H, Vorobiof, D, Martin, M, Slabber, C F, Ciruelos, E, Bourbouloux, E, Mendiola, C, Delgado, F M, Colin, C, Aslanis, V, Fumoleau, P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360552/ https://www.ncbi.nlm.nih.gov/pubmed/17031408 http://dx.doi.org/10.1038/sj.bjc.6603347

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