Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo

The unique properties of the tumour microenvironment can be exploited by using recombinant anaerobic clostridial spores as highly selective gene delivery vectors. Although several recombinant Clostridium species have been generated during the past decade, their efficacy has been limited. Our goal wa...

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Detalles Bibliográficos
Autores principales: Theys, J, Pennington, O, Dubois, L, Anlezark, G, Vaughan, T, Mengesha, A, Landuyt, W, Anné, J, Burke, P J, Dûrre, P, Wouters, B G, Minton, N P, Lambin, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360559/
https://www.ncbi.nlm.nih.gov/pubmed/17024128
http://dx.doi.org/10.1038/sj.bjc.6603367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360559/
https://www.ncbi.nlm.nih.gov/pubmed/17024128
http://dx.doi.org/10.1038/sj.bjc.6603367

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