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Targeting sphingosine-1-phosphate for cancer therapy
This review summarises some important new findings that implicate sphingosine-1-phosphate (S1P) as a potent tumorigenic and angiogenic agent released from cancerous tumours into the tumour microenvironment. Also explored is the novel concept that bioactive lipid signalling molecules, like S1P, can t...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360571/ https://www.ncbi.nlm.nih.gov/pubmed/17024123 http://dx.doi.org/10.1038/sj.bjc.6603400 |