Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations

A new synthetic isothiocyanate (ITC) derivative, ethyl 4-isothiocyanatobutanoate (E-4IB), appeared to be an effective modulator of cellular proliferation and potent inducer of apoptosis. In cooperation with cisplatin, this compound exerted synergistic effects in human ovarian carcinoma A2780 cells....

Descripción completa

Detalles Bibliográficos
Autores principales: Bodo, J, Hunakova, L, Kvasnicka, P, Jakubikova, J, Duraj, J, Kasparkova, J, Sedlak, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360594/
https://www.ncbi.nlm.nih.gov/pubmed/17060935
http://dx.doi.org/10.1038/sj.bjc.6603434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360594/
https://www.ncbi.nlm.nih.gov/pubmed/17060935
http://dx.doi.org/10.1038/sj.bjc.6603434

Ejemplares similares