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A positive role for PEA3 in HER2-mediated breast tumour progression

Overexpression of HER2 is associated with an adverse prognosis in breast cancer. Despite this, the mechanism of its transcriptional regulation remains poorly understood. PEA3, a MAP kinase (MAPK)-activated member of the Ets transcription factor family has been implicated in the transcriptional regul...

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Detalles Bibliográficos
Autores principales: Myers, E, Hill, A D K, Kelly, G, McDermott, E W, O'Higgins, N J, Young, L S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360603/
https://www.ncbi.nlm.nih.gov/pubmed/17060941
http://dx.doi.org/10.1038/sj.bjc.6603427