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Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

Tumour-associated macrophages, TAMs, play a pivotal role in tumour growth and metastasis by promoting tumour angiogenesis. Treatment with clodronate encapsulated in liposomes (clodrolip) efficiently depleted these phagocytic cells in the murine F9 teratocarcinoma and human A673 rhabdomyosarcoma mous...

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Detalles Bibliográficos
Autores principales:	Zeisberger, S M, Odermatt, B, Marty, C, Zehnder-Fjällman, A H M, Ballmer-Hofer, K, Schwendener, R A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360657/ https://www.ncbi.nlm.nih.gov/pubmed/16832418 http://dx.doi.org/10.1038/sj.bjc.6603240

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