Cargando…
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
Cellular senescence, the irreversible proliferative arrest seen in somatic cells after a limited number of divisions, is considered a crucial barrier to cancer, but direct evidence for this in vivo was lacking until recently. The best-known form of human cell senescence is attributed to telomere sho...
Autores principales: | Gray-Schopfer, V C, Cheong, S C, Chong, H, Chow, J, Moss, T, Abdel-Malek, Z A, Marais, R, Wynford-Thomas, D, Bennett, D C |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360676/ https://www.ncbi.nlm.nih.gov/pubmed/16880792 http://dx.doi.org/10.1038/sj.bjc.6603283 |
Ejemplares similares
-
Creation of immortalised epithelial cells from ovarian endometrioma
por: Bono, Y, et al.
Publicado: (2012) -
Establishment of an immortalised human ovarian surface epithelial cell line without chromosomal instability
por: Maeda, T, et al.
Publicado: (2005) -
WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma
por: Rogers, H A, et al.
Publicado: (2012) -
TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion
por: Boecke, A, et al.
Publicado: (2013) -
Melanoma in congenital melanocytic naevi
por: Kinsler, V.A., et al.
Publicado: (2017)