Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis

Gastric cancer metastasised to the liver was found to overexpress HER2 at a significantly higher incidence than primary gastric cancers. The purpose of the present study was to investigate the possibility of molecular therapy targeting HER2 overexpression in gastric cancer liver metastasis. We devel...

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Detalles Bibliográficos
Autores principales: Yokoyama, H, Ikehara, Y, Kodera, Y, Ikehara, S, Yatabe, Y, Mochizuki, Y, Koike, M, Fujiwara, M, Nakao, A, Tatematsu, M, Nakanishi, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360749/
https://www.ncbi.nlm.nih.gov/pubmed/17088902
http://dx.doi.org/10.1038/sj.bjc.6603459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360749/
https://www.ncbi.nlm.nih.gov/pubmed/17088902
http://dx.doi.org/10.1038/sj.bjc.6603459

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