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Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer

To examine the significance of the methylation level of the p53 target and tumour suppressor genes apoptotic protease activating factor-1 (APAF-1) and death-associated protein kinase-1 (DAPK-1) in 80 microdissected tumour samples from transitional cell carcinoma (TCC) of the bladder and 80 tumour sa...

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Detalles Bibliográficos
Autores principales:	Christoph, F, Kempkensteffen, C, Weikert, S, Köllermann, J, Krause, H, Miller, K, Schostak, M, Schrader, M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360762/ https://www.ncbi.nlm.nih.gov/pubmed/17133271 http://dx.doi.org/10.1038/sj.bjc.6603482

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