The measurement and therapeutic implications of circulating tumour cells in breast cancer

Circulating tumours cells (CTCs) represent an important biologic link in the spread of breast cancer from primary to metastatic disease. CTCs are strong predictors of prognosis in patients with metastatic breast cancer. Research to date has focused on development of methods with adequate sensitivity...

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Detalles Bibliográficos
Autores principales: Smerage, J B, Hayes, D F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361069/
https://www.ncbi.nlm.nih.gov/pubmed/16317435
http://dx.doi.org/10.1038/sj.bjc.6602871
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author Smerage, J B
Hayes, D F
author_facet Smerage, J B
Hayes, D F
author_sort Smerage, J B
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description Circulating tumours cells (CTCs) represent an important biologic link in the spread of breast cancer from primary to metastatic disease. CTCs are strong predictors of prognosis in patients with metastatic breast cancer. Research to date has focused on development of methods with adequate sensitivity and specificity to reproducibly identify these rare events. Future research will focus on the biologic phenotypes of these cells with goals to understand mechanisms of metastasis, to identify novel therapeutic targets, and to monitor response to therapy.
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spelling pubmed-23610692009-09-10 The measurement and therapeutic implications of circulating tumour cells in breast cancer Smerage, J B Hayes, D F Br J Cancer Minireview Circulating tumours cells (CTCs) represent an important biologic link in the spread of breast cancer from primary to metastatic disease. CTCs are strong predictors of prognosis in patients with metastatic breast cancer. Research to date has focused on development of methods with adequate sensitivity and specificity to reproducibly identify these rare events. Future research will focus on the biologic phenotypes of these cells with goals to understand mechanisms of metastasis, to identify novel therapeutic targets, and to monitor response to therapy. Nature Publishing Group 2006-01-16 2005-11-29 /pmc/articles/PMC2361069/ /pubmed/16317435 http://dx.doi.org/10.1038/sj.bjc.6602871 Text en Copyright © 2006 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Smerage, J B
Hayes, D F
The measurement and therapeutic implications of circulating tumour cells in breast cancer
title The measurement and therapeutic implications of circulating tumour cells in breast cancer
title_full The measurement and therapeutic implications of circulating tumour cells in breast cancer
title_fullStr The measurement and therapeutic implications of circulating tumour cells in breast cancer
title_full_unstemmed The measurement and therapeutic implications of circulating tumour cells in breast cancer
title_short The measurement and therapeutic implications of circulating tumour cells in breast cancer
title_sort measurement and therapeutic implications of circulating tumour cells in breast cancer
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361069/
https://www.ncbi.nlm.nih.gov/pubmed/16317435
http://dx.doi.org/10.1038/sj.bjc.6602871
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