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Epidermal growth factor receptor dimerization status determines skin toxicity to HER-kinase targeted therapies

Skin toxicity, a common drug-related adverse event observed in cancer patients treated with epidermal growth factor receptor (EGFR)-directed therapies is rarely seen with therapies targeting HER2. This study reports the significance of the EGFR and HER2 dimerization status in skin with regard to the...

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Detalles Bibliográficos
Autores principales:	Laux, I, Jain, A, Singh, S, Agus, D B
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361091/ https://www.ncbi.nlm.nih.gov/pubmed/16306877 http://dx.doi.org/10.1038/sj.bjc.6602875

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