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Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS) – novel predictors for response and survival in gastric cancer patients

To evaluate the predictive value of a panel of gene polymorphisms involved in metabolism of 5-FU and cisplatin on clinical outcome in advanced gastric cancer patients. A total of 52 patients were enrolled in this study. DNA was extracted from paraffin-embedded tumour specimen. Genotypes were determi...

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Detalles Bibliográficos
Autores principales: Goekkurt, E, Hoehn, S, Wolschke, C, Wittmer, C, Stueber, C, Hossfeld, D K, Stoehlmacher, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361118/
https://www.ncbi.nlm.nih.gov/pubmed/16317430
http://dx.doi.org/10.1038/sj.bjc.6602891

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