Tumours and tremors: how PTEN regulation underlies both

Mutations of the tumour suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10) are seen in many human cancers. However, dysregulation of PTEN may be involved in other disease states such as Parkinson's disease. This minireview describes recent work examining PTEN regulation a...

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Detalles Bibliográficos
Autores principales: Kim, R H, Mak, T W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361204/
https://www.ncbi.nlm.nih.gov/pubmed/16495927
http://dx.doi.org/10.1038/sj.bjc.6602994
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author Kim, R H
Mak, T W
author_facet Kim, R H
Mak, T W
author_sort Kim, R H
collection PubMed
description Mutations of the tumour suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10) are seen in many human cancers. However, dysregulation of PTEN may be involved in other disease states such as Parkinson's disease. This minireview describes recent work examining PTEN regulation and its implications for the development of both cancer and neurodegenerative disease.
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spelling pubmed-23612042009-09-10 Tumours and tremors: how PTEN regulation underlies both Kim, R H Mak, T W Br J Cancer Minireview Mutations of the tumour suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10) are seen in many human cancers. However, dysregulation of PTEN may be involved in other disease states such as Parkinson's disease. This minireview describes recent work examining PTEN regulation and its implications for the development of both cancer and neurodegenerative disease. Nature Publishing Group 2006-03-13 2006-02-21 /pmc/articles/PMC2361204/ /pubmed/16495927 http://dx.doi.org/10.1038/sj.bjc.6602994 Text en Copyright © 2006 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Kim, R H
Mak, T W
Tumours and tremors: how PTEN regulation underlies both
title Tumours and tremors: how PTEN regulation underlies both
title_full Tumours and tremors: how PTEN regulation underlies both
title_fullStr Tumours and tremors: how PTEN regulation underlies both
title_full_unstemmed Tumours and tremors: how PTEN regulation underlies both
title_short Tumours and tremors: how PTEN regulation underlies both
title_sort tumours and tremors: how pten regulation underlies both
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361204/
https://www.ncbi.nlm.nih.gov/pubmed/16495927
http://dx.doi.org/10.1038/sj.bjc.6602994
work_keys_str_mv AT kimrh tumoursandtremorshowptenregulationunderliesboth
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