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A selective retinoid X receptor agonist bexarotene (LGD1069, targretin) inhibits angiogenesis and metastasis in solid tumours

The present study determined the influence of a retinoid X receptor agonist bexarotene on angiogenesis and metastasis in solid tumours. In the experimental lung metastasis xenograft models, treatment with bexarotene inhibited the development of the lung tumour nodule formation compared to control. I...

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Detalles Bibliográficos
Autores principales: Yen, W-C, Prudente, R Y, Corpuz, M R, Negro-Vilar, A, Lamph, W W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361207/
https://www.ncbi.nlm.nih.gov/pubmed/16495926
http://dx.doi.org/10.1038/sj.bjc.6602995