Cargando…

Net1 and Myeov: computationally identified mediators of gastric cancer

Gastric adenocarcinoma (GA) is a significant cause of mortality worldwide. The molecular mechanisms of GA remain poorly characterised. Our aim was to characterise the functional activity of the computationally identified genes, NET 1 and MYEOV in GA. Digital Differential Display was used to identify...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leyden, J, Murray, D, Moss, A, Arumuguma, M, Doyle, E, McEntee, G, O'Keane, C, Doran, P, MacMathuna, P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361249/ https://www.ncbi.nlm.nih.gov/pubmed/16552434 http://dx.doi.org/10.1038/sj.bjc.6603054

Ejemplares similares

NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer
por: Murray, D, et al.
Publicado: (2008)

MYEOV (myeloma overexpressed gene) drives colon cancer cell migration and is regulated by PGE(2)
por: Lawlor, Garrett, et al.
Publicado: (2010)

A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer
por: Bennett, Gayle, et al.
Publicado: (2011)

In silico gene expression analysis – an overview
por: Murray, David, et al.
Publicado: (2007)

In Silico Promoter Analysis can Predict Genes of Functional Relevance in Cell Proliferation: Validation in a Colon Cancer Model
por: Moss, Alan C., et al.
Publicado: (2007)

Expression of neuroepithelial transforming gene 1 is enhanced in oesophageal cancer and mediates an invasive tumour cell phenotype
por: Lahiff, Conor, et al.
Publicado: (2013)

Identification of MYEOV-Associated Gene Network as a Potential Therapeutic Target in Pancreatic Cancer
por: Chen, Yu, et al.
Publicado: (2022)

Parallel functional testing identifies enhancers active in early postnatal mouse brain
por: Lambert, Jason T, et al.
Publicado: (2021)

Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance
por: Jeyapalan, J N, et al.
Publicado: (2011)

Activating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum
por: Matsubara, A, et al.
Publicado: (2015)

Fibulin 1 is downregulated through promoter hypermethylation in gastric cancer
por: Cheng, Y Y, et al.
Publicado: (2008)

Gene expression profiling identifies different sub-types of retinoblastoma
por: Kapatai, G, et al.
Publicado: (2013)

Cross talk between hedgehog and epithelial–mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers
por: Ohta, H, et al.
Publicado: (2009)

MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-β pathway in NSCLC
por: Fang, Lishan, et al.
Publicado: (2018)

Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival
por: Belien, J A M, et al.
Publicado: (2009)

Familial risk for gastric carcinoma: an updated study from Sweden
por: Hemminki, K, et al.
Publicado: (2007)

Transgenesis and web resources in quail
por: Serralbo, Olivier, et al.
Publicado: (2020)

Microarray comparative genomic hybridisation analysis of intraocular uveal melanomas identifies distinctive imbalances associated with loss of chromosome 3
por: Hughes, S, et al.
Publicado: (2005)

Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia
por: Honda, T, et al.
Publicado: (2004)

Myeloma Overexpressed 2 (Myeov2) Regulates L11 Subnuclear Localization through Nedd8 Modification
por: Ebina, Manato, et al.
Publicado: (2013)

Tumour-necrosis factor-A polymorphisms and gastric cancer risk: a meta-analysis
por: Gorouhi, F, et al.
Publicado: (2008)

Gene expression profiles in human gastric cancer: expression of maspin correlates with lymph node metastasis
por: Terashima, M, et al.
Publicado: (2005)

DNA copy number changes in young gastric cancer patients with special reference to chromosome 19
por: Varis, A, et al.
Publicado: (2003)

Differential gene expression profiles of gastric cancer cells established from primary tumour and malignant ascites
por: Sakakura, C, et al.
Publicado: (2002)

RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
por: Endoh, M, et al.
Publicado: (2005)

Gene expression profiling identifies distinct molecular subgroups of leiomyosarcoma with clinical relevance
por: Lee, Yin-Fai, et al.
Publicado: (2016)

Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers
por: Noda, H, et al.
Publicado: (2007)

Mutations in the ST7/RAY1/HELG locus rarely occur in primary colorectal, gastric, and hepatocellular carcinomas
por: Yoshimura, S, et al.
Publicado: (2003)

In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer
por: Perry, A S, et al.
Publicado: (2007)

KDM5A mutations identified in autism spectrum disorder using forward genetics
por: El Hayek, Lauretta, et al.
Publicado: (2020)

Integrating LASSO Feature Selection and Soft Voting Classifier to Identify Origins of Replication Sites
por: Yao, Yingying, et al.
Publicado: (2022)

Identifying the genetic basis of viral spillover using Lassa virus as a test case
por: Whitlock, Alexander O. B., et al.
Publicado: (2023)

Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis
por: Takeno, A, et al.
Publicado: (2008)

The MYEOV-MYC association promotes oncogenic miR-17/93-5p expression in pancreatic ductal adenocarcinoma
por: Shen, Hongzhang, et al.
Publicado: (2021)

Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma
por: Morris, M R, et al.
Publicado: (2008)

Chromosomal CGH identifies patients with a higher risk of relapse in neuroblastoma without MYCN amplification
por: Schleiermacher, G, et al.
Publicado: (2007)

Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling
por: Lambert, S R, et al.
Publicado: (2014)

Single-cell analysis of mosquito hemocytes identifies signatures of immune cell subtypes and cell differentiation
por: Kwon, Hyeogsun, et al.
Publicado: (2021)

Pan-genome analysis identifies intersecting roles for Pseudomonas specialized metabolites in potato pathogen inhibition
por: Pacheco-Moreno, Alba, et al.
Publicado: (2021)

Study of seven single-nucleotide polymorphisms identified in East Asians for association with obesity in a Taiwanese population
por: Huang, Wei-Hsin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_smf50kj95v06nsvf0m9t7e40h1