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Co expression of SCF and KIT in gastrointestinal stromal tumours (GISTs) suggests an autocrine/paracrine mechanism

KIT is a tyrosine kinase receptor expressed by several tumours, which has for specific ligand the stem cell factor (SCF). KIT is the main oncogene in gastrointestinal stromal tumours (GISTs), and gain-of-function KIT mutations are present in 70% of these tumours. The aim of the study was to measure...

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Detalles Bibliográficos
Autores principales:	Théou-Anton, N, Tabone, S, Brouty-Boyé, D, Saffroy, R, Ronnstrand, L, Lemoine, A, Emile, J-F
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361250/ https://www.ncbi.nlm.nih.gov/pubmed/16570044 http://dx.doi.org/10.1038/sj.bjc.6603063

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