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Phase I/II study of S-1 combined with irinotecan for metastatic advanced gastric cancer

A dose-escalation study of irinotecan (CPT-11) combined with S-1, an oral dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, was performed to determine the maximum-tolerated dose (MTD), recommended dose (RD), dose-limiting toxicities (DLTs), and objective response rate (RR) in advanced gas...

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Detalles Bibliográficos
Autores principales:	Inokuchi, M, Yamashita, T, Yamada, H, Kojima, K, Ichikawa, W, Nihei, Z, Kawano, T, Sugihara, K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361252/ https://www.ncbi.nlm.nih.gov/pubmed/16570038 http://dx.doi.org/10.1038/sj.bjc.6603072

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