Cargando…

Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer

Erlotinib (Tarceva™, OSI-774), a potent epidermal growth factor receptor tyrosine kinase inhibitor (EGFR), was evaluated in a phase II study to assess its activity in patients with metastatic colorectal cancer. In all, 38 patients with metastatic colorectal cancer were treated with erlotinib at a co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Townsley, C A, Major, P, Siu, L L, Dancey, J, Chen, E, Pond, G R, Nicklee, T, Ho, J, Hedley, D, Tsao, M, Moore, M J, Oza, A M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361254/ https://www.ncbi.nlm.nih.gov/pubmed/16570047 http://dx.doi.org/10.1038/sj.bjc.6603055

Ejemplares similares

A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas
por: Duran, I, et al.
Publicado: (2006)

Disposition of Erlotinib and Its Metabolite OSI420 in a Patient with High Bilirubin Levels
por: Czejka, M., et al.
Publicado: (2013)

Workshop on the Use of OSI for Libraries
por: Cailloux, J M
Publicado: (1989)

Is OSI too late?
por: Carpenter, B E
Publicado: (1989)

Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation
por: Thappali, Satheeshmanikandan R. S., et al.
Publicado: (2012)

Randomised Phase 2 study of maintenance linsitinib (OSI-906) in combination with erlotinib compared with placebo plus erlotinib after platinum-based chemotherapy in patients with advanced non-small cell lung cancer
por: Ciuleanu, Tudor-Eliade, et al.
Publicado: (2017)

Differential effects of depleting agents on cytoplasmic and nuclear non-protein sulphydryls: a fluorescence image cytometry study.
por: Thomas, M., et al.
Publicado: (1995)

Data communications, computer networks and OSI
por: Halsall, Fred
Publicado: (1988)

Building 774: open for business
por: CERN Bulletin
Publicado: (2015)

Association between tissue hypoxia and elevated non-protein sulphydryl concentrations in human cervical carcinoma xenografts
por: Moreno-Merlo, F, et al.
Publicado: (1999)

Recurrent and Metastatic Cutaneous Squamous Cell Carcinomas in a Cohort of 774 Patients in Finland
por: KORHONEN, Niina, et al.
Publicado: (2020)

Ribbon-cutting ceremony for Building 774
por: Corinne Pralavorio
Publicado: (2015)

Fundamental particles: Bat 774 at CERN
por: Soppelsa, Francesco, et al.
Publicado: (2016)

The elegant lines of the new Building 774
por: Anaïs Schaeffer
Publicado: (2012)

Combination effects of ellagic acid with erlotinib in a Ba/F3 cell line expressing EGFR H773_V774 insH mutation
por: Xie, Chuanqi, et al.
Publicado: (2020)

Solar superstorm of AD 774 recorded subannually by Arctic tree rings
por: Uusitalo, J., et al.
Publicado: (2018)

OSI-NSAP: un indirizzamento gerarchico per il garr
por: Delpino, F, et al.
Publicado: (1995)

Sistema interactivo del modelo de referencia OSI /
por: Contreras Martínez, Ruth Selene
Publicado: (2004)

Next stop OSI: transition to DECnet phase V
por: Heagerty, D
Publicado: (1990)

OSI explained: end-to-end computer communication standards
por: Henshall, John, et al.
Publicado: (1988)

Dose escalation to rash for erlotinib plus gemcitabine for metastatic pancreatic cancer: the phase II RACHEL study
por: Van Cutsem, E, et al.
Publicado: (2014)

Author Correction: Solar superstorm of AD 774 recorded subannually by Arctic tree rings
por: Uusitalo, J., et al.
Publicado: (2019)

774. Sexual Behaviors and Attitudes of Intimate Partners of Ebola Survivors
por: Cunningham, Hannah M, et al.
Publicado: (2020)

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis
por: Andreu, Nuria, et al.
Publicado: (2017)

Systemic BCG‐osis following intravesical BCG instillation for bladder carcinoma
por: Liaw, Frank, et al.
Publicado: (2017)

Online Support and Intervention for Child Anxiety (OSI): Development and Usability Testing
por: Hill, Claire, et al.
Publicado: (2022)

Single Arm, Phase II Study of Cisplatin, Docetaxel, and Erlotinib in Patients with Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinomas
por: William, William N., et al.
Publicado: (2018)

774. Trivia Game for Learning Zoonotic Diseases in Pre-clinical Medical Curriculum
por: Moreland, Celeste L, et al.
Publicado: (2023)

Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib
por: Flaig, T W, et al.
Publicado: (2010)

774. Extrapulmonary Tuberculosis: Impact of Early Diagnosis and Treatment on Mortality
por: Walayat, Saqib, et al.
Publicado: (2018)

Platinum-Catalyzed Reduction of DMF by 1,1,3,3-Tetramethyldisiloxane, HMeSi(2)OSiMe(2)H: New Intermediates HSiMe(2)OSiMe(2)OCH(2)NMe(2) and HSiMe(2)(OSiMe(2))(3)OCH(2)NMe(2) and Their Further Chemical Reactivity
por: Martinez, Jorge L., et al.
Publicado: (2014)

The effect of sarcopenia on erlotinib therapy in patients with metastatic lung adenocarcinoma
por: Topcu, Atakan, et al.
Publicado: (2022)

A Randomized Phase II Study of Linsitinib (OSI-906) Versus Topotecan in Patients With Relapsed Small-Cell Lung Cancer
por: Chiappori, Alberto A., et al.
Publicado: (2016)

Libraries, networks and OSI: a review, with a report on North American developments
por: Dempsey, Lorcan
Publicado: (1991)

DECnet routing transition from phase IV to phase V/OSI in Japan
por: Yuasa, F, et al.
Publicado: (1994)

The modulated low-temperature structure of malayaite, CaSnOSiO(4)
por: Malcherek, Thomas, et al.
Publicado: (2020)

Phase II trial of modified FOLFOX6 and erlotinib in patients with metastatic or advanced adenocarcinoma of the oesophagus and gastro-oesophageal junction
por: Wainberg, Z A, et al.
Publicado: (2011)

Ramucirumab Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Untreated Metastatic EGFR-Mutated NSCLC: RELAY Japanese Subset
por: Nishio, Kazuto, et al.
Publicado: (2021)

Ramucirumab plus erlotinib versus placebo plus erlotinib in previously untreated EGFR-mutated metastatic non-small-cell lung cancer (RELAY): exploratory analysis of next-generation sequencing results
por: Garon, E.B., et al.
Publicado: (2023)

Resistance of LHC main bus bar splices at room temperature and at 77.4 K
por: Heck, S, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_k2nsnq4u4sfjf8npen0o3ldnbk