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HER2 expression as a potential marker for response to therapy targeted to the EGFR

Since human epidermal growth factor receptor 2 (HER2) is known to participate with the epidermal growth factor receptor (EGFR) in mitogenic signalling, we hypothesised that HER2 overexpression might indicate responsiveness to EGFR targeted therapies. MCF7 breast cancer cells transfected with the HER...

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Detalles Bibliográficos
Autores principales:	Emlet, D R, Schwartz, R, Brown, K A, Pollice, A A, Smith, C A, Shackney, S E
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361260/ https://www.ncbi.nlm.nih.gov/pubmed/16622439 http://dx.doi.org/10.1038/sj.bjc.6603078

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