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Cell-free and cell-bound circulating DNA in breast tumours: DNA quantification and analysis of tumour-related gene methylation

Tumour development is characterised by the increased circulating DNA (cirDNA) concentration and by tumour-related changes in blood plasma DNA. Concentration of cirDNA and methylation of RARβ2, RASSF1A and HIC-1 gene promoters were investigated in cell-free and cell-surface-bound fractions from healt...

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Detalles Bibliográficos
Autores principales:	Skvortsova, T E, Rykova, E Y, Tamkovich, S N, Bryzgunova, O E, Starikov, A V, Kuznetsova, N P, Vlassov, V V, Laktionov, P P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361269/ https://www.ncbi.nlm.nih.gov/pubmed/16641902 http://dx.doi.org/10.1038/sj.bjc.6603117

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