Controlled clinical trials in cancer pain. How controlled should they be? A qualitative systematic review

This qualitative systematic review of the clinical methodology used in randomised, controlled trials of oral opioids (morphine, hydromorphone, oxycodone) for cancer pain underlines the difficulties of good pain research in palliative care. The current literature lacks placebo-controlled superiority...

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Detalles Bibliográficos
Autores principales: Bell, R F, Wisløff, T, Eccleston, C, Kalso, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361312/
https://www.ncbi.nlm.nih.gov/pubmed/16705312
http://dx.doi.org/10.1038/sj.bjc.6603162
Descripción
Sumario:This qualitative systematic review of the clinical methodology used in randomised, controlled trials of oral opioids (morphine, hydromorphone, oxycodone) for cancer pain underlines the difficulties of good pain research in palliative care. The current literature lacks placebo-controlled superiority trials. Recommendations for future research are discussed.

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