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Prostaglandin E(2) stimulates progression-related gene expression in early colorectal adenoma cells

Upregulation of cyclooxygenase-2 (COX-2) and prostaglandin-dependent vascularisation in small adenomatous polyps is an essential part of colon carcinogenesis. To study the underlying cellular mechanisms, LT97 and Caco2 human colorectal tumour cells not expressing endogenous COX-2 were exposed to 1 μ...

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Detalles Bibliográficos
Autores principales: Mauritz, I, Westermayer, S, Marian, B, Erlach, N, Grusch, M, Holzmann, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361321/
https://www.ncbi.nlm.nih.gov/pubmed/16685273
http://dx.doi.org/10.1038/sj.bjc.6603146

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