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Prostaglandin E(2) stimulates progression-related gene expression in early colorectal adenoma cells
Upregulation of cyclooxygenase-2 (COX-2) and prostaglandin-dependent vascularisation in small adenomatous polyps is an essential part of colon carcinogenesis. To study the underlying cellular mechanisms, LT97 and Caco2 human colorectal tumour cells not expressing endogenous COX-2 were exposed to 1 μ...
Autores principales: | Mauritz, I, Westermayer, S, Marian, B, Erlach, N, Grusch, M, Holzmann, K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361321/ https://www.ncbi.nlm.nih.gov/pubmed/16685273 http://dx.doi.org/10.1038/sj.bjc.6603146 |
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