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Epigenetic inactivation of TCF2 in ovarian cancer and various cancer cell lines
Transcription factor 2 gene (TCF2) encodes hepatocyte nuclear factor 1β (HNF1β), a transcription factor associated with development and metabolism. Mutation of TCF2 has been observed in renal cell cancer, and by screening aberrantly methylated genes, we have now identified TCF2 as a target for epige...
Autores principales: | Terasawa, K, Toyota, M, Sagae, S, Ogi, K, Suzuki, H, Sonoda, T, Akino, K, Maruyama, R, Nishikawa, N, Imai, K, Shinomura, Y, Saito, T, Tokino, T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361363/ https://www.ncbi.nlm.nih.gov/pubmed/16479257 http://dx.doi.org/10.1038/sj.bjc.6602984 |
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