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Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial

The epidermal growth factor receptor (EGFR), which participates in signalling pathways that are deregulated in cancer cells, is frequently mutated in colorectal-cancer cells. Cetuximab is a monoclonal antibody that specifically blocks the EGFR. We evaluated the efficacy of cetuximab in weekly combin...

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Detalles Bibliográficos
Autores principales:	Vincenzi, B, Santini, D, Rabitti, C, Coppola, R, Beomonte Zobel, B, Trodella, L, Tonini, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361373/ https://www.ncbi.nlm.nih.gov/pubmed/16508634 http://dx.doi.org/10.1038/sj.bjc.6603018

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