Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE

In this minireview, we briefly revisit the Drosophila Notch and epidermal growth factor receptor pathways, and relate to the relationship between them. We then mainly focus on the involvement of Groucho (Gro)/TLE, a global developmental corepressor, in these pathways. In particular, we discuss Gro/T...

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Detalles Bibliográficos
Autores principales: Hasson, P, Paroush, Z
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361374/
https://www.ncbi.nlm.nih.gov/pubmed/16508633
http://dx.doi.org/10.1038/sj.bjc.6603019
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author Hasson, P
Paroush, Z
author_facet Hasson, P
Paroush, Z
author_sort Hasson, P
collection PubMed
description In this minireview, we briefly revisit the Drosophila Notch and epidermal growth factor receptor pathways, and relate to the relationship between them. We then mainly focus on the involvement of Groucho (Gro)/TLE, a global developmental corepressor, in these pathways. In particular, we discuss Gro/TLE's role at the junction between these two signal transduction cascades.
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spelling pubmed-23613742009-09-10 Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE Hasson, P Paroush, Z Br J Cancer Minireview In this minireview, we briefly revisit the Drosophila Notch and epidermal growth factor receptor pathways, and relate to the relationship between them. We then mainly focus on the involvement of Groucho (Gro)/TLE, a global developmental corepressor, in these pathways. In particular, we discuss Gro/TLE's role at the junction between these two signal transduction cascades. Nature Publishing Group 2006-03-27 2006-02-28 /pmc/articles/PMC2361374/ /pubmed/16508633 http://dx.doi.org/10.1038/sj.bjc.6603019 Text en Copyright © 2006 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Hasson, P
Paroush, Z
Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE
title Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE
title_full Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE
title_fullStr Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE
title_full_unstemmed Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE
title_short Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE
title_sort crosstalk between the egfr and other signalling pathways at the level of the global transcriptional corepressor groucho/tle
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361374/
https://www.ncbi.nlm.nih.gov/pubmed/16508633
http://dx.doi.org/10.1038/sj.bjc.6603019
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