The place of VEGF inhibition in the current management of renal cell carcinoma

Vascular endothelial growth factor (VEGF) is overexpressed in around 80% of patients with clear cell carcinoma of the kidney owing to the inactivation of von Hippel Lindau gene activity. VEGF stimulates angiogenesis and acts as an autocrine growth factor. A number of different agents are now availab...

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Detalles Bibliográficos
Autores principales: Nathan, P, Chao, D, Brock, C, Savage, P, Harries, M, Gore, M, Eisen, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361396/
https://www.ncbi.nlm.nih.gov/pubmed/16508632
http://dx.doi.org/10.1038/sj.bjc.6603025

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