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Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma

Promoter region hypermethylation and transcriptional silencing is a frequent cause of tumour suppressor gene (TSG) inactivation in many human cancers. Previously, to identify candidate epigenetically inactivated TSGs in renal cell carcinoma (RCC), we monitored changes in gene expression in four RCC...

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Detalles Bibliográficos
Autores principales:	Morris, M R, Gentle, D, Abdulrahman, M, Clarke, N, Brown, M, Kishida, T, Yao, M, Teh, B T, Latif, F, Maher, E R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361461/ https://www.ncbi.nlm.nih.gov/pubmed/18195710 http://dx.doi.org/10.1038/sj.bjc.6604180

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