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Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells

Multiple myeloma (MM) accounts for 1 % of all cancer deaths. Although treated aggressively, almost all myelomas eventually recur and become resistant to treatment. Atiprimod (2-(3-Diethylaminopropyl)-8,8-dipropyl-2-azaspiro[4,5] decane dimaleate) has exerted anti-inflammatory activities and inhibite...

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Detalles Bibliográficos
Autores principales:	Amit-Vazina, M, Shishodia, S, Harris, D, Van, Q, Wang, M, Weber, D, Alexanian, R, Talpaz, M, Aggarwal, B B, Estrov, Z
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361492/ https://www.ncbi.nlm.nih.gov/pubmed/15970928 http://dx.doi.org/10.1038/sj.bjc.6602637

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