Microarray comparative genomic hybridisation analysis of intraocular uveal melanomas identifies distinctive imbalances associated with loss of chromosome 3

Defining regions of genomic imbalance can identify genes involved in tumour development. Conventional cytogenetics has identified several nonrandom copy number alterations (CNA) in uveal melanomas (UVM), which include monosomy 3, chromosome 6 abnormalities and gain of 8q. To gain further insight int...

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Detalles Bibliográficos
Autores principales: Hughes, S, Damato, B E, Giddings, I, Hiscott, P S, Humphreys, J, Houlston, R S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361503/
https://www.ncbi.nlm.nih.gov/pubmed/16251874
http://dx.doi.org/10.1038/sj.bjc.6602834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361503/
https://www.ncbi.nlm.nih.gov/pubmed/16251874
http://dx.doi.org/10.1038/sj.bjc.6602834

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