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Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer
Activation of kinases signalling pathways contributes to various malignant phenotypes in human cancers, including breast tumour. To examine the possible activation of these signalling molecules, we examined the phosphorylation status in 12 protein kinases and transcription factors in normal primary...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361529/ https://www.ncbi.nlm.nih.gov/pubmed/16288304 http://dx.doi.org/10.1038/sj.bjc.6602862 |