RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer

RASSF2, a member of the RASSF1 family, has recently been identified as a potential tumour suppressor. We examined methylation status in multiple regions which included the CpG island and spanned the transcription start site of RASSF2 in 10 gastric cancer cell lines, as well as 78 primary gastric can...

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Detalles Bibliográficos
Autores principales: Endoh, M, Tamura, G, Honda, T, Homma, N, Terashima, M, Nishizuka, S, Motoyama, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361541/
https://www.ncbi.nlm.nih.gov/pubmed/16265349
http://dx.doi.org/10.1038/sj.bjc.6602854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361541/
https://www.ncbi.nlm.nih.gov/pubmed/16265349
http://dx.doi.org/10.1038/sj.bjc.6602854

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