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Serum CA19-9 response as a surrogate for clinical outcome in patients receiving fixed-dose rate gemcitabine for advanced pancreatic cancer
The use of serial serum measurements of the carbohydrate antigen 19-9 (CA19-9) to guide treatment decisions and serve as a surrogate end point in clinical trial design requires further validation. We investigated whether CA19-9 decline represents an accurate surrogate for survival and time to treatm...
Autores principales: | Ko, A H, Hwang, J, Venook, A P, Abbruzzese, J L, Bergsland, E K, Tempero, M A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361548/ https://www.ncbi.nlm.nih.gov/pubmed/15999098 http://dx.doi.org/10.1038/sj.bjc.6602687 |
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