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The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers

There is increased incidence of microsatellite instability (MSI) in patients who develop multiple primary colorectal cancers (CRC), although the association with hereditary nonpolyposis colon cancer (HNPCC) is unclear. This study aims to evaluate the underlying genetic cause of MSI in these patients...

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Detalles Bibliográficos
Autores principales: Lawes, D A, Pearson, T, SenGupta, S, Boulos, P B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361590/
https://www.ncbi.nlm.nih.gov/pubmed/16106253
http://dx.doi.org/10.1038/sj.bjc.6602708