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The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers
There is increased incidence of microsatellite instability (MSI) in patients who develop multiple primary colorectal cancers (CRC), although the association with hereditary nonpolyposis colon cancer (HNPCC) is unclear. This study aims to evaluate the underlying genetic cause of MSI in these patients...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361590/ https://www.ncbi.nlm.nih.gov/pubmed/16106253 http://dx.doi.org/10.1038/sj.bjc.6602708 |