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Endothelial apoptotic activity of angiocidin is dependent on its polyubiquitin binding activity

We recently cloned the full-length cDNA of a tumour-associated protein. The recombinant protein expressed in bacteria and referred to as angiocidin has potent antitumour activity in vivo and in vitro. Angiocidin inhibits tumour growth and angiogenesis by inducing apoptosis in endothelial cells. Base...

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Detalles Bibliográficos
Autores principales:	Dimitrov, S, Sabherwal, Y, Raymond, D D, L'Heureux, D Z, Lu, Q, Tuszynski, G P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361611/ https://www.ncbi.nlm.nih.gov/pubmed/16222312 http://dx.doi.org/10.1038/sj.bjc.6602773

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