Cancer chemoprevention: lessons learned and future directions

The concept of delaying or preventing epithelial transformation remains a viable and attainable goal for the future. Drug-based strategies for chemoprevention of the future may predominantly rely upon targeted therapies with tolerable but defined toxicities for treatment of individuals diagnosed wit...

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Detalles Bibliográficos
Autores principales: Brenner, D E, Gescher, A J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361630/
https://www.ncbi.nlm.nih.gov/pubmed/16160697
http://dx.doi.org/10.1038/sj.bjc.6602765
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author Brenner, D E
Gescher, A J
author_facet Brenner, D E
Gescher, A J
author_sort Brenner, D E
collection PubMed
description The concept of delaying or preventing epithelial transformation remains a viable and attainable goal for the future. Drug-based strategies for chemoprevention of the future may predominantly rely upon targeted therapies with tolerable but defined toxicities for treatment of individuals diagnosed with intraepithelial neoplasias. Foods, diet manipulation strategies, or nutraceuticals may be more appropriate to delay or prevent carcinogenesis progression in healthy populations with genetic or epidemiologic evidence of risk for future transformation.
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spelling pubmed-23616302009-09-10 Cancer chemoprevention: lessons learned and future directions Brenner, D E Gescher, A J Br J Cancer Minireview The concept of delaying or preventing epithelial transformation remains a viable and attainable goal for the future. Drug-based strategies for chemoprevention of the future may predominantly rely upon targeted therapies with tolerable but defined toxicities for treatment of individuals diagnosed with intraepithelial neoplasias. Foods, diet manipulation strategies, or nutraceuticals may be more appropriate to delay or prevent carcinogenesis progression in healthy populations with genetic or epidemiologic evidence of risk for future transformation. Nature Publishing Group 2005-10-03 2005-09-06 /pmc/articles/PMC2361630/ /pubmed/16160697 http://dx.doi.org/10.1038/sj.bjc.6602765 Text en Copyright © 2005 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Brenner, D E
Gescher, A J
Cancer chemoprevention: lessons learned and future directions
title Cancer chemoprevention: lessons learned and future directions
title_full Cancer chemoprevention: lessons learned and future directions
title_fullStr Cancer chemoprevention: lessons learned and future directions
title_full_unstemmed Cancer chemoprevention: lessons learned and future directions
title_short Cancer chemoprevention: lessons learned and future directions
title_sort cancer chemoprevention: lessons learned and future directions
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361630/
https://www.ncbi.nlm.nih.gov/pubmed/16160697
http://dx.doi.org/10.1038/sj.bjc.6602765
work_keys_str_mv AT brennerde cancerchemopreventionlessonslearnedandfuturedirections
AT gescheraj cancerchemopreventionlessonslearnedandfuturedirections

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