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Two randomised phase II trials of subcutaneous interleukin-2 and histamine dihydrochloride in patients with metastatic renal cell carcinoma
Histamine inhibits formation and release of phagocyte-derived reactive oxygen species, and thereby protects natural killer and T cells against oxidative damage. Thus, the addition of histamine may potentially improve the efficacy of interleukin-2 (IL-2). Two randomised phase II trials of IL-2 with o...
Autores principales: | Donskov, F, Middleton, M, Fode, K, Meldgaard, P, Mansoor, W, Lawrance, J, Thatcher, N, Nellemann, H, von der Maase, H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361635/ https://www.ncbi.nlm.nih.gov/pubmed/16136045 http://dx.doi.org/10.1038/sj.bjc.6602768 |
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