Sex hormones and oesophageal adenocarcinoma: influence of childbearing?

The male predominance of oesophageal adenocarcinoma might be explained by oestrogen protection in women. If true, female patients might have sex hormonal disturbances rendering impaired fertility. The influence of childbearing on the risk of oesophageal adenocarcinoma was investigated in a Swedish p...

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Detalles Bibliográficos
Autores principales: Lagergren, J, Jansson, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361653/
https://www.ncbi.nlm.nih.gov/pubmed/16189516
http://dx.doi.org/10.1038/sj.bjc.6602810
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author Lagergren, J
Jansson, C
author_facet Lagergren, J
Jansson, C
author_sort Lagergren, J
collection PubMed
description The male predominance of oesophageal adenocarcinoma might be explained by oestrogen protection in women. If true, female patients might have sex hormonal disturbances rendering impaired fertility. The influence of childbearing on the risk of oesophageal adenocarcinoma was investigated in a Swedish population-based case (n=63) -control (n=141) study. Childless women were not at increased risk compared to childbearing (OR=0.82; 95% CI=0.25–2.72), as neither were women with 0–1 children compared to women with at least three children (OR=0.93; 95% CI=0.35–2.49). In conclusion, we found no inverse assciation between childbearing and oesophageal adenocarcinoma.
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spelling pubmed-23616532009-09-10 Sex hormones and oesophageal adenocarcinoma: influence of childbearing? Lagergren, J Jansson, C Br J Cancer Clinical Study The male predominance of oesophageal adenocarcinoma might be explained by oestrogen protection in women. If true, female patients might have sex hormonal disturbances rendering impaired fertility. The influence of childbearing on the risk of oesophageal adenocarcinoma was investigated in a Swedish population-based case (n=63) -control (n=141) study. Childless women were not at increased risk compared to childbearing (OR=0.82; 95% CI=0.25–2.72), as neither were women with 0–1 children compared to women with at least three children (OR=0.93; 95% CI=0.35–2.49). In conclusion, we found no inverse assciation between childbearing and oesophageal adenocarcinoma. Nature Publishing Group 2005-10-17 2005-09-27 /pmc/articles/PMC2361653/ /pubmed/16189516 http://dx.doi.org/10.1038/sj.bjc.6602810 Text en Copyright © 2005 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Clinical Study
Lagergren, J
Jansson, C
Sex hormones and oesophageal adenocarcinoma: influence of childbearing?
title Sex hormones and oesophageal adenocarcinoma: influence of childbearing?
title_full Sex hormones and oesophageal adenocarcinoma: influence of childbearing?
title_fullStr Sex hormones and oesophageal adenocarcinoma: influence of childbearing?
title_full_unstemmed Sex hormones and oesophageal adenocarcinoma: influence of childbearing?
title_short Sex hormones and oesophageal adenocarcinoma: influence of childbearing?
title_sort sex hormones and oesophageal adenocarcinoma: influence of childbearing?
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361653/
https://www.ncbi.nlm.nih.gov/pubmed/16189516
http://dx.doi.org/10.1038/sj.bjc.6602810
work_keys_str_mv AT lagergrenj sexhormonesandoesophagealadenocarcinomainfluenceofchildbearing
AT janssonc sexhormonesandoesophagealadenocarcinomainfluenceofchildbearing

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