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Meta-analysis of cancer incidence in children born after assisted reproductive technologies
A meta-analysis was performed on 11 cohort studies of Assisted Reproductive Technologies (ART) and subsequent childhood cancer, published up to February 2005, which reported comparable, nonoverlapping data, and then restricted to eight studies which presented a similar research design. The overall S...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361681/ https://www.ncbi.nlm.nih.gov/pubmed/16234814 http://dx.doi.org/10.1038/sj.bjc.6602838 |
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author | Raimondi, S Pedotti, P Taioli, E |
author_facet | Raimondi, S Pedotti, P Taioli, E |
author_sort | Raimondi, S |
collection | PubMed |
description | A meta-analysis was performed on 11 cohort studies of Assisted Reproductive Technologies (ART) and subsequent childhood cancer, published up to February 2005, which reported comparable, nonoverlapping data, and then restricted to eight studies which presented a similar research design. The overall Standardised Incidence Ratio was 1.33 (95% CI 0.62–2.85), and 0.77 (95% CI 0.41–1.42) when the analysis was restricted to eight studies. No evidence of publication bias was observed for the overall analysis. The data are consistent with a lack of increase in risk of childhood cancer, though the amount of data on ART and cancer is still limited; larger multicentric studies as well as a pooled analysis on the available data are warranted. |
format | Text |
id | pubmed-2361681 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-23616812009-09-10 Meta-analysis of cancer incidence in children born after assisted reproductive technologies Raimondi, S Pedotti, P Taioli, E Br J Cancer Epidemiology A meta-analysis was performed on 11 cohort studies of Assisted Reproductive Technologies (ART) and subsequent childhood cancer, published up to February 2005, which reported comparable, nonoverlapping data, and then restricted to eight studies which presented a similar research design. The overall Standardised Incidence Ratio was 1.33 (95% CI 0.62–2.85), and 0.77 (95% CI 0.41–1.42) when the analysis was restricted to eight studies. No evidence of publication bias was observed for the overall analysis. The data are consistent with a lack of increase in risk of childhood cancer, though the amount of data on ART and cancer is still limited; larger multicentric studies as well as a pooled analysis on the available data are warranted. Nature Publishing Group 2005-10-31 2005-10-18 /pmc/articles/PMC2361681/ /pubmed/16234814 http://dx.doi.org/10.1038/sj.bjc.6602838 Text en Copyright © 2005 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Epidemiology Raimondi, S Pedotti, P Taioli, E Meta-analysis of cancer incidence in children born after assisted reproductive technologies |
title | Meta-analysis of cancer incidence in children born after assisted reproductive technologies |
title_full | Meta-analysis of cancer incidence in children born after assisted reproductive technologies |
title_fullStr | Meta-analysis of cancer incidence in children born after assisted reproductive technologies |
title_full_unstemmed | Meta-analysis of cancer incidence in children born after assisted reproductive technologies |
title_short | Meta-analysis of cancer incidence in children born after assisted reproductive technologies |
title_sort | meta-analysis of cancer incidence in children born after assisted reproductive technologies |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361681/ https://www.ncbi.nlm.nih.gov/pubmed/16234814 http://dx.doi.org/10.1038/sj.bjc.6602838 |
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