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Reorganisation of Wnt-response pathways in colorectal tumorigenesis

In most colorectal tumours, APC mutation stabilises β-catenin and mimics elements of Wnt growth factor signalling, but the high frequency of epigenetic loss of Wnt antagonists indicates an additional role for ligand-mediated Wnt signalling. Here, we have investigated the expression of key components...

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Detalles Bibliográficos
Autores principales:	Caldwell, G M, Jones, C E, Soon, Y, Warrack, R, Morton, D G, Matthews, G M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361695/ https://www.ncbi.nlm.nih.gov/pubmed/18414471 http://dx.doi.org/10.1038/sj.bjc.6604327

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