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The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice
Retinoids, vitamin A analogues that bind to retinoic acid receptor (RAR) or retinoid X receptor (RXR), play important roles in regulating cell proliferation, apoptosis, and differentiation. Recently, RXR-selective ligands, also referred to as rexinoids, have been investigated as potential chemopreve...
Autores principales: | Li, Y, Zhang, Y, Hill, J, Kim, H-T, Shen, Q, Bissonnette, R P, Lamph, W W, Brown, P H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361704/ https://www.ncbi.nlm.nih.gov/pubmed/18362934 http://dx.doi.org/10.1038/sj.bjc.6604320 |
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