Cargando…
Targeting of Pseudorabies Virus Structural Proteins to Axons Requires Association of the Viral Us9 Protein with Lipid Rafts
The pseudorabies virus (PRV) Us9 protein plays a central role in targeting viral capsids and glycoproteins to axons of dissociated sympathetic neurons. As a result, Us9 null mutants are defective in anterograde transmission of infection in vivo. However, it is unclear how Us9 promotes axonal sorting...
Autores principales: | Lyman, Mathew G., Curanovic, Dusica, Enquist, Lynn W. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361720/ https://www.ncbi.nlm.nih.gov/pubmed/18483549 http://dx.doi.org/10.1371/journal.ppat.1000065 |
Ejemplares similares
-
The axonal sorting activity of pseudorabies virus Us9 protein depends on the state of neuronal maturation
por: Tanneti, Nikhila S., et al.
Publicado: (2020) -
Role of Us9 Phosphorylation in Axonal Sorting and Anterograde Transport of Pseudorabies Virus
por: Kratchmarov, Radomir, et al.
Publicado: (2013) -
A Pseudorabies Virus Serine/Threonine Kinase, US3, Promotes Retrograde Transport in Axons via Akt/mToRC1
por: Esteves, Andrew D., et al.
Publicado: (2022) -
The Neuropathic Itch Caused by Pseudorabies Virus
por: Laval, Kathlyn, et al.
Publicado: (2020) -
Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport
por: Adamou, Steven, et al.
Publicado: (2023)