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Integrin β1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo
Integrin β1 is both overexpressed and in an ‘active’ conformation in vulval squamous cell carcinomas (VSCCs) compared to matched normal skin. To investigate the significance of integrin β1 deregulation we stably knocked-down integrin β1 expression in the VSCC cell line A431. In vitro analysis reveal...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361733/ https://www.ncbi.nlm.nih.gov/pubmed/15597106 http://dx.doi.org/10.1038/sj.bjc.6602255 |