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Integrin β1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo

Integrin β1 is both overexpressed and in an ‘active’ conformation in vulval squamous cell carcinomas (VSCCs) compared to matched normal skin. To investigate the significance of integrin β1 deregulation we stably knocked-down integrin β1 expression in the VSCC cell line A431. In vitro analysis reveal...

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Detalles Bibliográficos
Autores principales:	Brockbank, E C, Bridges, J, Marshall, C J, Sahai, E
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361733/ https://www.ncbi.nlm.nih.gov/pubmed/15597106 http://dx.doi.org/10.1038/sj.bjc.6602255

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