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Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression
Tumour-associated angiogenesis is partly regulated by the hypoxia-inducible factor (HIF) pathway. Endocrine tumours are highly vascularised and the molecular mechanisms of their angiogenesis are not fully delineated. The aim of this study is to evaluate angiogenesis and expression of HIF-related mol...
Autores principales: | Couvelard, A, O'Toole, D, Turley, H, Leek, R, Sauvanet, A, Degott, C, Ruszniewski, P, Belghiti, J, Harris, A L, Gatter, K, Pezzella, F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361752/ https://www.ncbi.nlm.nih.gov/pubmed/15558070 http://dx.doi.org/10.1038/sj.bjc.6602245 |
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