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Intensity-modulated radiation therapy: emerging cancer treatment technology

The use of intensity-modulated radiation therapy (IMRT) is rapidly advancing in the field of radiation oncology. Intensity-modulated radiation therapy allows for improved dose conformality, thereby affording the potential to decrease the spectrum of normal tissue toxicities associated with IMRT. Pre...

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Detalles Bibliográficos
Autores principales: Hong, T S, Ritter, M A, Tomé, W A, Harari, P M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361760/
https://www.ncbi.nlm.nih.gov/pubmed/15856036
http://dx.doi.org/10.1038/sj.bjc.6602577
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author Hong, T S
Ritter, M A
Tomé, W A
Harari, P M
author_facet Hong, T S
Ritter, M A
Tomé, W A
Harari, P M
author_sort Hong, T S
collection PubMed
description The use of intensity-modulated radiation therapy (IMRT) is rapidly advancing in the field of radiation oncology. Intensity-modulated radiation therapy allows for improved dose conformality, thereby affording the potential to decrease the spectrum of normal tissue toxicities associated with IMRT. Preliminary results with IMRT are quite promising; however, the clinical data is relatively immature and overall patient numbers remain small. High-quality IMRT requires intensive physics support and detailed knowledge of three-dimensional anatomy and patterns of tumour spread. This review focuses on basic principles, and highlights the clinical implementation of IMRT in head and neck and prostate cancer.
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spelling pubmed-23617602009-09-10 Intensity-modulated radiation therapy: emerging cancer treatment technology Hong, T S Ritter, M A Tomé, W A Harari, P M Br J Cancer Minireview The use of intensity-modulated radiation therapy (IMRT) is rapidly advancing in the field of radiation oncology. Intensity-modulated radiation therapy allows for improved dose conformality, thereby affording the potential to decrease the spectrum of normal tissue toxicities associated with IMRT. Preliminary results with IMRT are quite promising; however, the clinical data is relatively immature and overall patient numbers remain small. High-quality IMRT requires intensive physics support and detailed knowledge of three-dimensional anatomy and patterns of tumour spread. This review focuses on basic principles, and highlights the clinical implementation of IMRT in head and neck and prostate cancer. Nature Publishing Group 2005-05-23 2005-04-26 /pmc/articles/PMC2361760/ /pubmed/15856036 http://dx.doi.org/10.1038/sj.bjc.6602577 Text en Copyright © 2005 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Hong, T S
Ritter, M A
Tomé, W A
Harari, P M
Intensity-modulated radiation therapy: emerging cancer treatment technology
title Intensity-modulated radiation therapy: emerging cancer treatment technology
title_full Intensity-modulated radiation therapy: emerging cancer treatment technology
title_fullStr Intensity-modulated radiation therapy: emerging cancer treatment technology
title_full_unstemmed Intensity-modulated radiation therapy: emerging cancer treatment technology
title_short Intensity-modulated radiation therapy: emerging cancer treatment technology
title_sort intensity-modulated radiation therapy: emerging cancer treatment technology
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361760/
https://www.ncbi.nlm.nih.gov/pubmed/15856036
http://dx.doi.org/10.1038/sj.bjc.6602577
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