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Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS
In contrast to cutaneous melanoma, there is no evidence that BRAF mutations are involved in the activation of the mitogen-activated protein kinase (MAPK) pathway in uveal melanoma, although there is increasing evidence that this pathway is activated frequently in the latter tumours. In this study, w...
Autores principales: | Zuidervaart, W, van Nieuwpoort, F, Stark, M, Dijkman, R, Packer, L, Borgstein, A-M, Pavey, S, van der Velden, P, Out, C, Jager, M J, Hayward, N K, Gruis, N A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361800/ https://www.ncbi.nlm.nih.gov/pubmed/15928660 http://dx.doi.org/10.1038/sj.bjc.6602598 |
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