Gene expression signatures for colorectal cancer microsatellite status and HNPCC

The majority of microsatellite instable (MSI) colorectal cancers are sporadic, but a subset belongs to the syndrome hereditary nonpolyposis colorectal cancer (HNPCC). Microsatellite instability is caused by dysfunction of the mismatch repair (MMR) system that leads to a mutator phenotype, and MSI is...

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Detalles Bibliográficos
Autores principales: Kruhøffer, M, Jensen, J L, Laiho, P, Dyrskjøt, L, Salovaara, R, Arango, D, Birkenkamp-Demtroder, K, Sørensen, F B, Christensen, L L, Buhl, L, Mecklin, J-P, Järvinen, H, Thykjaer, T, Wikman, F P, Bech-Knudsen, F, Juhola, M, Nupponen, N N, Laurberg, S, Andersen, C L, Aaltonen, L A, Ørntoft, T F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361815/
https://www.ncbi.nlm.nih.gov/pubmed/15956967
http://dx.doi.org/10.1038/sj.bjc.6602621

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