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Phase I trial of oral S-1 combined with gemcitabine in metastatic pancreatic cancer

The objective of this study was to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of S-1, an oral fluorouracil derivative, combined with gemcitabine, the current standard treatment for advanced pancreatic cancer (APC). The subjects were histopathologically proven APC...

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Detalles Bibliográficos
Autores principales: Nakamura, K, Yamaguchi, T, Ishihara, T, Kobayashi, A, Tadenuma, H, Sudo, K, Kato, H, Saisho, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361829/
https://www.ncbi.nlm.nih.gov/pubmed/15942632
http://dx.doi.org/10.1038/sj.bjc.6602644