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Phase I trial of oral S-1 combined with gemcitabine in metastatic pancreatic cancer
The objective of this study was to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of S-1, an oral fluorouracil derivative, combined with gemcitabine, the current standard treatment for advanced pancreatic cancer (APC). The subjects were histopathologically proven APC...
Autores principales: | Nakamura, K, Yamaguchi, T, Ishihara, T, Kobayashi, A, Tadenuma, H, Sudo, K, Kato, H, Saisho, H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361829/ https://www.ncbi.nlm.nih.gov/pubmed/15942632 http://dx.doi.org/10.1038/sj.bjc.6602644 |
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